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Human Flt3L Generates Dendritic Cells from Canine Peripheral Blood Precursors: Implications for a Dog Glioma Clinical Trial

BACKGROUND: Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and carries a dismal prognosis. We have developed a conditional cytotoxic/immunotherapeutic approach using adenoviral vectors (Ads) encoding the immunostimulatory cytokine, human soluble fms-like tyrosine kina...

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Detalles Bibliográficos
Autores principales: Xiong, Weidong, Candolfi, Marianela, Liu, Chunyan, Muhammad, A. K. M. Ghulam, Yagiz, Kader, Puntel, Mariana, Moore, Peter F., Avalos, Julie, Young, John D., Khan, Dorothy, Donelson, Randy, Pluhar, G. Elizabeth, Ohlfest, John R., Wawrowsky, Kolja, Lowenstein, Pedro R., Castro, Maria G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884015/
https://www.ncbi.nlm.nih.gov/pubmed/20552015
http://dx.doi.org/10.1371/journal.pone.0011074