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Induction of Premature Senescence by Hsp90 Inhibition in Small Cell Lung Cancer
BACKGROUND: The molecular chaperone Hsp90 is a promising new target in cancer therapy and selective Hsp90 inhibitors are currently in clinical trials. Previously these inhibitors have been reported to induce either cell cycle arrest or cell death in cancer cells. Whether the cell cycle arrest is rev...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884022/ https://www.ncbi.nlm.nih.gov/pubmed/20552022 http://dx.doi.org/10.1371/journal.pone.0011076 |