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Radiotherapy Suppresses Angiogenesis in Mice through TGF-βRI/ALK5-Dependent Inhibition of Endothelial Cell Sprouting

BACKGROUND: Radiotherapy is widely used to treat cancer. While rapidly dividing cancer cells are naturally considered the main target of radiotherapy, emerging evidence indicates that radiotherapy also affects endothelial cell functions, and possibly also their angiogenic capacity. In spite of its c...

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Detalles Bibliográficos
Autores principales: Imaizumi, Natsuko, Monnier, Yan, Hegi, Monika, Mirimanoff, René-Olivier, Rüegg, Curzio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884035/
https://www.ncbi.nlm.nih.gov/pubmed/20552031
http://dx.doi.org/10.1371/journal.pone.0011084