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Radiotherapy Suppresses Angiogenesis in Mice through TGF-βRI/ALK5-Dependent Inhibition of Endothelial Cell Sprouting
BACKGROUND: Radiotherapy is widely used to treat cancer. While rapidly dividing cancer cells are naturally considered the main target of radiotherapy, emerging evidence indicates that radiotherapy also affects endothelial cell functions, and possibly also their angiogenic capacity. In spite of its c...
Autores principales: | Imaizumi, Natsuko, Monnier, Yan, Hegi, Monika, Mirimanoff, René-Olivier, Rüegg, Curzio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884035/ https://www.ncbi.nlm.nih.gov/pubmed/20552031 http://dx.doi.org/10.1371/journal.pone.0011084 |
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