A Vaccine Encoding Conserved Promiscuous HIV CD4 Epitopes Induces Broad T Cell Responses in Mice Transgenic to Multiple Common HLA Class II Molecules

Current HIV vaccine approaches are focused on immunogens encoding whole HIV antigenic proteins that mainly elicit cytotoxic CD8+ responses. Mounting evidence points toward a critical role for CD4+ T cells in the control of immunodeficiency virus replication, probably due to cognate help. Vaccine-ind...

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Detalles Bibliográficos
Autores principales: Ribeiro, Susan Pereira, Rosa, Daniela Santoro, Fonseca, Simone Gonçalves, Mairena, Eliane Conti, Postól, Edilberto, Oliveira, Sergio Costa, Guilherme, Luiza, Kalil, Jorge, Cunha-Neto, Edecio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884037/
https://www.ncbi.nlm.nih.gov/pubmed/20552033
http://dx.doi.org/10.1371/journal.pone.0011072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884037/
https://www.ncbi.nlm.nih.gov/pubmed/20552033
http://dx.doi.org/10.1371/journal.pone.0011072

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