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G-stack modulated probe intensities on expression arrays - sequence corrections and signal calibration
BACKGROUND: The brightness of the probe spots on expression microarrays intends to measure the abundance of specific mRNA targets. Probes with runs of at least three guanines (G) in their sequence show abnormal high intensities which reflect rather probe effects than target concentrations. This G-bi...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884167/ https://www.ncbi.nlm.nih.gov/pubmed/20423484 http://dx.doi.org/10.1186/1471-2105-11-207 |