Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-κB()

Liver injury associated with exposure to therapeutic agents that undergo hepatic metabolism can involve the formation of reactive metabolites. These may cause redox perturbation which can result in oxidative stress as well as protein modification leading to activation or inhibition of cellular trans...

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Detalles Bibliográficos
Autores principales: Chia, Alvin J.L., Goldring, Christopher E., Kitteringham, Neil R., Wong, Shi Quan, Morgan, Paul, Park, B. Kevin
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884179/
https://www.ncbi.nlm.nih.gov/pubmed/20416283
http://dx.doi.org/10.1016/j.bcp.2010.04.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884179/
https://www.ncbi.nlm.nih.gov/pubmed/20416283
http://dx.doi.org/10.1016/j.bcp.2010.04.004

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