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Endangered Species Hold Clues to Human Evolution

We report that 18 conserved, and by extension functional, elements in the human genome are the result of retroposon insertions that are evolving under purifying selection in mammals. We show evidence that 1 of the 18 elements regulates the expression of ASXL3 during development by encoding an altern...

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Detalles Bibliográficos
Autores principales: Lowe, Craig B., Bejerano, Gill, Salama, Sofie R., Haussler, David
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884192/
https://www.ncbi.nlm.nih.gov/pubmed/20332163
http://dx.doi.org/10.1093/jhered/esq016