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Endangered Species Hold Clues to Human Evolution
We report that 18 conserved, and by extension functional, elements in the human genome are the result of retroposon insertions that are evolving under purifying selection in mammals. We show evidence that 1 of the 18 elements regulates the expression of ASXL3 during development by encoding an altern...
Autores principales: | Lowe, Craig B., Bejerano, Gill, Salama, Sofie R., Haussler, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884192/ https://www.ncbi.nlm.nih.gov/pubmed/20332163 http://dx.doi.org/10.1093/jhered/esq016 |
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