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ADP Compartmentation Analysis Reveals Coupling between Pyruvate Kinase and ATPases in Heart Muscle

Cardiomyocytes have intracellular diffusion restrictions, which spatially compartmentalize ADP and ATP. However, the models that predict diffusion restrictions have used data sets generated in rat heart permeabilized fibers, where diffusion distances may be heterogeneous. This is avoided by using is...

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Detalles Bibliográficos
Autores principales: Sepp, Mervi, Vendelin, Marko, Vija, Heiki, Birkedal, Rikke
Formato: Texto
Lenguaje:English
Publicado: The Biophysical Society 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884246/
https://www.ncbi.nlm.nih.gov/pubmed/20550890
http://dx.doi.org/10.1016/j.bpj.2010.03.025