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Phylogenetic assessment of alignments reveals neglected tree signal in gaps
BACKGROUND: The alignment of biological sequences is of chief importance to most evolutionary and comparative genomics studies, yet the two main approaches used to assess alignment accuracy have flaws: reference alignments are derived from the biased sample of proteins with known structure, and simu...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884540/ https://www.ncbi.nlm.nih.gov/pubmed/20370897 http://dx.doi.org/10.1186/gb-2010-11-4-r37 |