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Experimental determination of translational starts using peptide mass mapping and tandem mass spectrometry within the proteome of Mycobacterium tuberculosis

Identification of protein translation start sites is largely a bioinformatics exercise, with relatively few confirmed by N-terminal sequencing. Translation start site determination is critical for defining both the protein sequence and the upstream DNA which may contain regulatory motifs. It is demo...

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Detalles Bibliográficos
Autores principales: Rison, Stuart C. G., Mattow, Jens, Jungblut, Peter R., Stoker, Neil G.
Formato: Texto
Lenguaje:English
Publicado: Microbiology Society 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884946/
https://www.ncbi.nlm.nih.gov/pubmed/17259624
http://dx.doi.org/10.1099/mic.0.2006/001537-0