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Occurrence, function and evolutionary origins of ‘2A-like’ sequences in virus genomes

2A is an oligopeptide sequence mediating a ribosome ‘skipping’ effect, producing an apparent ‘cleavage’ of polyproteins. First identified and characterized in picornaviruses, ‘2A-like’ sequences are found in other mammalian viruses and a wide range of insect viruses. Databases were analysed using a...

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Detalles Bibliográficos
Autores principales: Luke, Garry A., de Felipe, Pablo, Lukashev, Alexander, Kallioinen, Susanna E., Bruno, Elizabeth A., Ryan, Martin D.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885027/
https://www.ncbi.nlm.nih.gov/pubmed/18343847
http://dx.doi.org/10.1099/vir.0.83428-0