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A historical analysis of herpes simplex virus promoter activation in vivo reveals distinct populations of latently infected neurones

Herpes simplex virus type 1 (HSV-1) has the capacity to establish a life-long latent infection in sensory neurones and also to periodically reactivate from these cells. Since mutant viruses defective for immediate-early (IE) expression retain the capacity for latency establishment it is widely assum...

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Detalles Bibliográficos
Autores principales: Proença, João T., Coleman, Heather M., Connor, Viv, Winton, Douglas J., Efstathiou, Stacey
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885028/
https://www.ncbi.nlm.nih.gov/pubmed/19008381
http://dx.doi.org/10.1099/vir.0.2008/005066-0