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Substitution of the myristoylation signal of human immunodeficiency virus type 1 Pr55(Gag) with the phospholipase C-δ1 pleckstrin homology domain results in infectious pseudovirion production
The matrix domain (MA) of human immunodeficiency virus type 1 Pr55(Gag) is covalently modified with a myristoyl group that mediates efficient viral production. However, the role of myristoylation, particularly in the viral entry process, remains uninvestigated. This study replaced the myristoylation...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885030/ https://www.ncbi.nlm.nih.gov/pubmed/19008404 http://dx.doi.org/10.1099/vir.0.2008/004820-0 |