Mumps virus Enders strain is sensitive to interferon (IFN) despite encoding a functional IFN antagonist

Although the Enders strain of mumps virus (MuV) encodes a functional V protein that acts as an interferon (IFN) antagonist, in multi-cycle growth assays MuV Enders grew poorly in naïve (‘IFN-competent’ Hep2) cells but grew to high titres in ‘IFN-compromised’ Hep2 cells. Even so, the growth rate of M...

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Detalles Bibliográficos
Autores principales: Young, D. F., Galiano, M. C., Lemon, K., Chen, Y.-H., Andrejeva, J., Duprex, W. P., Rima, B. K., Randall, R. E.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2009
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885035/
https://www.ncbi.nlm.nih.gov/pubmed/19625458
http://dx.doi.org/10.1099/vir.0.013722-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885035/
https://www.ncbi.nlm.nih.gov/pubmed/19625458
http://dx.doi.org/10.1099/vir.0.013722-0

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