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Acidic residues in the membrane-proximal stalk region of vaccinia virus protein B5 are required for glycosaminoglycan-mediated disruption of the extracellular enveloped virus outer membrane

The extracellular enveloped virus (EEV) form of vaccinia virus (VACV) is surrounded by two lipid envelopes. This presents a topological problem for virus entry into cells, because a classical fusion event would only release a virion surrounded by a single envelope into the cell. Recently, we describ...

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Detalles Bibliográficos
Autores principales: Roberts, Kim L., Breiman, Adrien, Carter, Gemma C., Ewles, Helen A., Hollinshead, Michael, Law, Mansun, Smith, Geoffrey L.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885056/
https://www.ncbi.nlm.nih.gov/pubmed/19264647
http://dx.doi.org/10.1099/vir.0.009092-0