The Epstein–Barr virus lytic cycle activator Zta interacts with methylated ZRE in the promoter of host target gene egr1

Activation of the host gene egr1 is essential for the lytic replication of Epstein–Barr virus (EBV). egr1 is activated by Zta (BZLF1, ZEBRA). Zta interacts directly with DNA through a series of closely related Zta-response elements (ZREs). Here we dissect the mechanism used by Zta to interact with t...

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Detalles Bibliográficos
Autores principales: Heather, James, Flower, Kirsty, Isaac, Samine, Sinclair, Alison J.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2009
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885059/
https://www.ncbi.nlm.nih.gov/pubmed/19264650
http://dx.doi.org/10.1099/vir.0.007922-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885059/
https://www.ncbi.nlm.nih.gov/pubmed/19264650
http://dx.doi.org/10.1099/vir.0.007922-0

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