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The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on behavioural responses to nicotine

RATIONALE: Previous studies have shown that blockade of metabotropic glutamate 5 receptors (mGluR5) results in inhibition of nicotine self-administration in experimental animals. However, these studies have not established the behavioural mechanisms which mediate these effects or the extent to which...

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Detalles Bibliográficos
Autores principales: Tronci, Valeria, Vronskaya, Svetlana, Montgomery, Nicholas, Mura, Daniela, Balfour, David J. K.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885299/
https://www.ncbi.nlm.nih.gov/pubmed/20422403
http://dx.doi.org/10.1007/s00213-010-1868-x