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Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2

BACKGROUND: Platelets are associated with HIV in the blood of infected individuals and might modulate viral dissemination, particularly if the virus is directly transmitted into the bloodstream. The C-type lectin DC-SIGN and the novel HIV attachment factor CLEC-2 are expressed by platelets and facil...

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Detalles Bibliográficos
Autores principales: Chaipan, Chawaree, Steffen, Imke, Tsegaye, Theodros Solomon, Bertram, Stephanie, Glowacka, Ilona, Kato, Yukinari, Schmökel, Jan, Münch, Jan, Simmons, Graham, Gerardy-Schahn, Rita, Pöhlmann, Stefan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885308/
https://www.ncbi.nlm.nih.gov/pubmed/20482880
http://dx.doi.org/10.1186/1742-4690-7-47