Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P

BACKGROUND: Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that typically causes asymptomatic infections in healthy individuals but may lead to serious complications in newborns and immunodeficient individuals. The emergence of drug-resistant strains of HCMV has posed a need for the develo...

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Detalles Bibliográficos
Autores principales: Zhang, WenJun, Li, HongJian, Li, YueQin, Zeng, ZhiFeng, Li, ShiQian, Zhang, Xin, Zou, Yi, Zhou, TianHong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885339/
https://www.ncbi.nlm.nih.gov/pubmed/20482805
http://dx.doi.org/10.1186/1743-422X-7-100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885339/
https://www.ncbi.nlm.nih.gov/pubmed/20482805
http://dx.doi.org/10.1186/1743-422X-7-100

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