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Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P

BACKGROUND: Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that typically causes asymptomatic infections in healthy individuals but may lead to serious complications in newborns and immunodeficient individuals. The emergence of drug-resistant strains of HCMV has posed a need for the develo...

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Detalles Bibliográficos
Autores principales:	Zhang, WenJun, Li, HongJian, Li, YueQin, Zeng, ZhiFeng, Li, ShiQian, Zhang, Xin, Zou, Yi, Zhou, TianHong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885339/ https://www.ncbi.nlm.nih.gov/pubmed/20482805 http://dx.doi.org/10.1186/1743-422X-7-100

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