Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors

BACKGROUND: The orally active quinoline-3-carboxamide tasquinimod [ABR-215050; CAS number 254964-60-8), which currently is in a phase II-clinical trial in patients against metastatic prostate cancer, exhibits anti-tumor activity via inhibition of tumor angiogenesis in human and rodent tumors. To fur...

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Detalles Bibliográficos
Autores principales: Olsson, Anders, Björk, Anders, Vallon-Christersson, Johan, Isaacs, John T, Leanderson, Tomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885345/
https://www.ncbi.nlm.nih.gov/pubmed/20470445
http://dx.doi.org/10.1186/1476-4598-9-107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885345/
https://www.ncbi.nlm.nih.gov/pubmed/20470445
http://dx.doi.org/10.1186/1476-4598-9-107

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