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The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model
BACKGROUND: Androgens bind to the androgen receptor (AR) in prostate cells and are essential survival factors for healthy prostate epithelium. Most untreated prostate cancers retain some dependence upon the AR and respond, at least transiently, to androgen ablation therapy. However, the relationship...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885348/ https://www.ncbi.nlm.nih.gov/pubmed/20406442 http://dx.doi.org/10.1186/1745-6150-5-24 |