Cargando…

Pantothenate Kinase 1 Is Required to Support the Metabolic Transition from the Fed to the Fasted State

Coenzyme A (CoA) biosynthesis is regulated by the pantothenate kinases (PanK), of which there are four active isoforms. The PanK1 isoform is selectively expressed in liver and accounted for 40% of the total PanK activity in this organ. CoA synthesis was limited using a Pank1 (−/−) knockout mouse mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Leonardi, Roberta, Rehg, Jerold E., Rock, Charles O., Jackowski, Suzanne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885419/
https://www.ncbi.nlm.nih.gov/pubmed/20559429
http://dx.doi.org/10.1371/journal.pone.0011107