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Pantothenate Kinase 1 Is Required to Support the Metabolic Transition from the Fed to the Fasted State
Coenzyme A (CoA) biosynthesis is regulated by the pantothenate kinases (PanK), of which there are four active isoforms. The PanK1 isoform is selectively expressed in liver and accounted for 40% of the total PanK activity in this organ. CoA synthesis was limited using a Pank1 (−/−) knockout mouse mod...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885419/ https://www.ncbi.nlm.nih.gov/pubmed/20559429 http://dx.doi.org/10.1371/journal.pone.0011107 |