HIF-1alpha and HIF-2alpha Are Differentially Activated in Distinct Cell Populations in Retinal Ischaemia

BACKGROUND: Hypoxia plays a key role in ischaemic and neovascular disorders of the retina. Cellular responses to oxygen are mediated by hypoxia-inducible transcription factors (HIFs) that are stabilised in hypoxia and induce the expression of a diverse range of genes. The purpose of this study was t...

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Detalles Bibliográficos
Autores principales: Mowat, Freya M., Luhmann, Ulrich F. O., Smith, Alexander J., Lange, Clemens, Duran, Yanai, Harten, Sarah, Shukla, Deepa, Maxwell, Patrick H., Ali, Robin R., Bainbridge, James W. B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885428/
https://www.ncbi.nlm.nih.gov/pubmed/20559438
http://dx.doi.org/10.1371/journal.pone.0011103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885428/
https://www.ncbi.nlm.nih.gov/pubmed/20559438
http://dx.doi.org/10.1371/journal.pone.0011103

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