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A Ubiquitin-Binding Domain in Cockayne Syndrome B Required for Transcription-Coupled Nucleotide Excision Repair

Transcription-coupled nucleotide excision repair (TC-NER) allows RNA polymerase II (RNAPII)-blocking lesions to be rapidly removed from the transcribed strand of active genes. Defective TCR in humans is associated with Cockayne syndrome (CS), typically caused by defects in either CSA or CSB. Here, w...

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Detalles Bibliográficos
Autores principales: Anindya, Roy, Mari, Pierre-Olivier, Kristensen, Ulrik, Kool, Hanneke, Giglia-Mari, Giuseppina, Mullenders, Leon H., Fousteri, Maria, Vermeulen, Wim, Egly, Jean-Marc, Svejstrup, Jesper Q.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885502/
https://www.ncbi.nlm.nih.gov/pubmed/20541997
http://dx.doi.org/10.1016/j.molcel.2010.04.017