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Heterologous expression of linoleic acid isomerase from Propionibacterium acnes and anti-proliferative activity of recombinant trans-10, cis-12 conjugated linoleic acid

The linoleic acid isomerase enzyme from Propionibacterium acnes responsible for bioconversion of linoleic acid to trans-10, cis-12 conjugated linoleic acid (t10, c12 CLA) was cloned and overexpressed in Lactococcus lactis and Escherichia coli, resulting in between 30 and 50 % conversion rates of the...

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Detalles Bibliográficos
Autores principales: Rosberg-Cody, Eva, Johnson, Mark C., Fitzgerald, Gerald F., Ross, Paul R., Stanton, Catherine
Formato: Texto
Lenguaje:English
Publicado: Microbiology Society 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885616/
https://www.ncbi.nlm.nih.gov/pubmed/17660413
http://dx.doi.org/10.1099/mic.0.2006/001966-0