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Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus virulence

Camelpox virus (CMLV) gene 176R encodes a protein with sequence similarity to murine schlafen (m-slfn) proteins. In vivo, short and long members of the m-slfn family inhibited T-cell development, whereas in vitro, only short m-slfns caused arrest of fibroblast growth. CMLV 176 protein (v-slfn) is mo...

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Detalles Bibliográficos
Autores principales: Gubser, Caroline, Goodbody, Rory, Ecker, Andrea, Brady, Gareth, O'Neill, Luke A. J., Jacobs, Nathalie, Smith, Geoffrey L.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885618/
https://www.ncbi.nlm.nih.gov/pubmed/17485525
http://dx.doi.org/10.1099/vir.0.82748-0