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Evaluation of signal peptide prediction algorithms for identification of mycobacterial signal peptides using sequence data from proteomic methods

Secreted proteins play an important part in the pathogenicity of Mycobacterium tuberculosis, and are the primary source of vaccine and diagnostic candidates. A majority of these proteins are exported via the signal peptidase I-dependent pathway, and have a signal peptide that is cleaved off during t...

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Detalles Bibliográficos
Autores principales: Leversen, Nils Anders, de Souza, Gustavo A., Målen, Hiwa, Prasad, Swati, Jonassen, Inge, Wiker, Harald G.
Formato: Texto
Lenguaje:English
Publicado: Microbiology Society 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885676/
https://www.ncbi.nlm.nih.gov/pubmed/19389770
http://dx.doi.org/10.1099/mic.0.025270-0