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Gene Expression Patterns of Dengue Virus-Infected Children from Nicaragua Reveal a Distinct Signature of Increased Metabolism

BACKGROUND: Infection with dengue viruses (DENV) leads to a spectrum of disease outcomes. The pathophysiology of severe versus non-severe manifestations of DENV infection may be driven by host responses, which could be reflected in the transcriptional profiles of peripheral blood immune cells. METHO...

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Detalles Bibliográficos
Autores principales: Loke, P'ng, Hammond, Samantha N., Leung, Jacqueline M., Kim, Charles C., Batra, Sajeev, Rocha, Crisanta, Balmaseda, Angel, Harris, Eva
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886038/
https://www.ncbi.nlm.nih.gov/pubmed/20559541
http://dx.doi.org/10.1371/journal.pntd.0000710