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Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis

BACKGROUND: Silencing of normal gene expression occurs early in the apoptosis of neurons, well before the cell is committed to the death pathway, and has been extensively characterized in injured retinal ganglion cells. The causative mechanism of this widespread change in gene expression is unknown....

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Detalles Bibliográficos
Autores principales: Pelzel, Heather R, Schlamp, Cassandra L, Nickells, Robert W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886060/
https://www.ncbi.nlm.nih.gov/pubmed/20504333
http://dx.doi.org/10.1186/1471-2202-11-62