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Regulation of Amyloid Precursor Protein Processing by the Beclin 1 Complex

Autophagy is an intracellular degradation pathway that functions in protein and organelle turnover in response to starvation and cellular stress. Autophagy is initiated by the formation of a complex containing Beclin 1 (BECN1) and its binding partner Phosphoinositide-3-kinase, class 3 (PIK3C3). Rece...

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Detalles Bibliográficos
Autores principales: Jaeger, Philipp A., Pickford, Fiona, Sun, Chung-Huan, Lucin, Kurt M., Masliah, Eliezer, Wyss-Coray, Tony
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886067/
https://www.ncbi.nlm.nih.gov/pubmed/20559548
http://dx.doi.org/10.1371/journal.pone.0011102