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Regulation of Amyloid Precursor Protein Processing by the Beclin 1 Complex
Autophagy is an intracellular degradation pathway that functions in protein and organelle turnover in response to starvation and cellular stress. Autophagy is initiated by the formation of a complex containing Beclin 1 (BECN1) and its binding partner Phosphoinositide-3-kinase, class 3 (PIK3C3). Rece...
Autores principales: | Jaeger, Philipp A., Pickford, Fiona, Sun, Chung-Huan, Lucin, Kurt M., Masliah, Eliezer, Wyss-Coray, Tony |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886067/ https://www.ncbi.nlm.nih.gov/pubmed/20559548 http://dx.doi.org/10.1371/journal.pone.0011102 |
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