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Large-Scale Expression Analysis Reveals Distinct MicroRNA Profiles at Different Stages of Human Neurodevelopment

BACKGROUND: MicroRNAs (miRNAs) are short non-coding RNAs predicted to regulate one third of protein coding genes via mRNA targeting. In conjunction with key transcription factors, such as the repressor REST (RE1 silencing transcription factor), miRNAs play crucial roles in neurogenesis, which requir...

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Detalles Bibliográficos
Autores principales: Smith, Brandon, Treadwell, Julie, Zhang, Dongling, Ly, Dao, McKinnell, Iain, Walker, P. Roy, Sikorska, Marianna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886071/
https://www.ncbi.nlm.nih.gov/pubmed/20559549
http://dx.doi.org/10.1371/journal.pone.0011109