Assay Strategies for the Discovery and Validation of Therapeutics Targeting Brugia pahangi Hsp90

The chemotherapy of lymphatic filariasis relies upon drugs such as diethylcarbamazine and ivermectin that largely target the microfilarial stages of the parasite, necessitating continued treatment over the long reproductive life span of the adult worm. The identification of compounds that target adu...

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Detalles Bibliográficos
Autores principales: Taldone, Tony, Gillan, Victoria, Sun, Weilin, Rodina, Anna, Patel, Pallav, Maitland, Kirsty, O'Neill, Kerry, Chiosis, Gabriela, Devaney, Eileen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886105/
https://www.ncbi.nlm.nih.gov/pubmed/20559560
http://dx.doi.org/10.1371/journal.pntd.0000714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886105/
https://www.ncbi.nlm.nih.gov/pubmed/20559560
http://dx.doi.org/10.1371/journal.pntd.0000714

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