Endogenous Wnt/β-Catenin Signaling Is Required for Cardiac Differentiation in Human Embryonic Stem Cells

BACKGROUND: Wnt/β-catenin signaling is an important regulator of differentiation and morphogenesis that can also control stem cell fates. Our group has developed an efficient protocol to generate cardiomyocytes from human embryonic stem (ES) cells via induction with activin A and BMP4. METHODOLOGY/P...

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Detalles Bibliográficos
Autores principales: Paige, Sharon L., Osugi, Tomoaki, Afanasiev, Olga K., Pabon, Lil, Reinecke, Hans, Murry, Charles E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886114/
https://www.ncbi.nlm.nih.gov/pubmed/20559569
http://dx.doi.org/10.1371/journal.pone.0011134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886114/
https://www.ncbi.nlm.nih.gov/pubmed/20559569
http://dx.doi.org/10.1371/journal.pone.0011134

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