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Endogenous Wnt/β-Catenin Signaling Is Required for Cardiac Differentiation in Human Embryonic Stem Cells
BACKGROUND: Wnt/β-catenin signaling is an important regulator of differentiation and morphogenesis that can also control stem cell fates. Our group has developed an efficient protocol to generate cardiomyocytes from human embryonic stem (ES) cells via induction with activin A and BMP4. METHODOLOGY/P...
Autores principales: | Paige, Sharon L., Osugi, Tomoaki, Afanasiev, Olga K., Pabon, Lil, Reinecke, Hans, Murry, Charles E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886114/ https://www.ncbi.nlm.nih.gov/pubmed/20559569 http://dx.doi.org/10.1371/journal.pone.0011134 |
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