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Multiple roles and therapeutic implications of Akt signaling in cancer

The prominence of the PI3K-Akt signaling pathway in several tumors indicates a relationship with tumor grade and proliferation. Critical cellular processes are driven through this pathway. More detailed knowledge of the pathogenesis of tumors would enable us to design targeted drugs to block both me...

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Detalles Bibliográficos
Autores principales: Calvo, Emiliano, Bolós, Victoria, Grande, Enrique
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886325/
https://www.ncbi.nlm.nih.gov/pubmed/20616901