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Modelling the Response of FOXO Transcription Factors to Multiple Post-Translational Modifications Made by Ageing-Related Signalling Pathways

FOXO transcription factors are an important, conserved family of regulators of cellular processes including metabolism, cell-cycle progression, apoptosis and stress resistance. They are required for the efficacy of several of the genetic interventions that modulate lifespan. FOXO activity is regulat...

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Detalles Bibliográficos
Autores principales: Smith, Graham R., Shanley, Daryl P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886341/
https://www.ncbi.nlm.nih.gov/pubmed/20567500
http://dx.doi.org/10.1371/journal.pone.0011092