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Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair

Rapid plasma membrane resealing is essential for cellular survival. Earlier studies showed that plasma membrane repair requires Ca(2+)-dependent exocytosis of lysosomes and a rapid form of endocytosis that removes membrane lesions. However, the functional relationship between lysosomal exocytosis an...

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Detalles Bibliográficos
Autores principales: Tam, Christina, Idone, Vincent, Devlin, Cecilia, Fernandes, Maria Cecilia, Flannery, Andrew, He, Xingxuan, Schuchman, Edward, Tabas, Ira, Andrews, Norma W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886342/
https://www.ncbi.nlm.nih.gov/pubmed/20530211
http://dx.doi.org/10.1083/jcb.201003053