Cargando…

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

Posttranslational glutamylation of tubulin is present on selected subsets of microtubules in cells. Although the modification is expected to contribute to the spatial and temporal organization of the cytoskeleton, hardly anything is known about its functional relevance. Here we demonstrate that glut...

Descripción completa

Detalles Bibliográficos
Autores principales: Lacroix, Benjamin, van Dijk, Juliette, Gold, Nicholas D., Guizetti, Julien, Aldrian-Herrada, Gudrun, Rogowski, Krzysztof, Gerlich, Daniel W., Janke, Carsten
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886356/
https://www.ncbi.nlm.nih.gov/pubmed/20530212
http://dx.doi.org/10.1083/jcb.201001024