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Cis Interactions between Notch and Delta Generate Mutually Exclusive Signaling States

The Notch-Delta signaling pathway enables communication between neighboring cells during development1. It plays a critical role in the formation of ‘fine-grained’ patterns, generating distinct cell fates among groups of initially equivalent neighboring cells, and in sharply delineating neighboring r...

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Detalles Bibliográficos
Autores principales: Sprinzak, David, Lakhanpal, Amit, LeBon, Lauren, Santat, Leah A., Fontes, Michelle E., Anderson, Graham A., Garcia-Ojalvo, Jordi, Elowitz, Michael B.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886601/
https://www.ncbi.nlm.nih.gov/pubmed/20418862
http://dx.doi.org/10.1038/nature08959