From Sensors to Silencers: Quinoline- and Benzimidazole-Sulfonamides as Inhibitors for Zinc Proteases

[Image: see text] Derived from the extensive work in the area of small molecule zinc(II) ion sensors, chelating fragment libraries of quinoline- and benzimidazole-sulfonamides have been prepared and screened against several different zinc(II)-dependent matrix metalloproteinases (MMPs). The fragments...

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Detalles Bibliográficos
Autores principales: Rouffet, Matthieu, de Oliveira, César Augusto F., Udi, Yael, Agrawal, Arpita, Sagi, Irit, McCammon, J. Andrew, Cohen, Seth M.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886603/
https://www.ncbi.nlm.nih.gov/pubmed/20507095
http://dx.doi.org/10.1021/ja101088j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886603/
https://www.ncbi.nlm.nih.gov/pubmed/20507095
http://dx.doi.org/10.1021/ja101088j

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