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IRAK-M Regulates Chromatin Remodeling in Lung Macrophages during Experimental Sepsis

Sepsis results in a profound state of immunosuppression, which is temporally associated with impaired leukocyte function. The mechanism of leukocyte reprogramming in sepsis is incompletely understood. In this study, we explored mechanisms contributing to dysregulated inflammatory cytokine expression...

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Detalles Bibliográficos
Autores principales: Lyn-Kew, Kenneth, Rich, Eric, Zeng, Xianying, Wen, Haitao, Kunkel, Steven L., Newstead, Michael W., Bhan, Urvashi, Standiford, Theodore J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886833/
https://www.ncbi.nlm.nih.gov/pubmed/20585389
http://dx.doi.org/10.1371/journal.pone.0011145