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Bronchus-Associated Lymphoid Tissue (BALT) and Survival in a Vaccine Mouse Model of Tularemia

BACKGROUND: Francisella tularensis causes severe pulmonary disease, and nasal vaccination could be the ideal measure to effectively prevent it. Nevertheless, the efficacy of this type of vaccine is influenced by the lack of an effective mucosal adjuvant. METHODOLOGY/PRINCIPAL FINDINGS: Mice were imm...

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Detalles Bibliográficos
Autores principales: Chiavolini, Damiana, Rangel-Moreno, Javier, Berg, Gretchen, Christian, Kate, Oliveira-Nascimento, Laura, Weir, Susan, Alroy, Joseph, Randall, Troy D., Wetzler, Lee M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886834/
https://www.ncbi.nlm.nih.gov/pubmed/20585390
http://dx.doi.org/10.1371/journal.pone.0011156