“Forward Genetics” as a Method to Maximize Power and Cost-Efficiency in Studies of Human Complex Traits

There is increasing interest in methods to disentangle the relationship between genotype and (endo)phenotypes in human complex traits. We present a population-based method of increasing the power and cost-efficiency of studies by selecting random individuals with a particular genotype and then asses...

Descripción completa

Detalles Bibliográficos
Autores principales: Boks, M. P. M., Derks, E. M., Dolan, C. V., Kahn, R. S., Ophoff, R. A.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886904/
https://www.ncbi.nlm.nih.gov/pubmed/20232132
http://dx.doi.org/10.1007/s10519-010-9348-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886904/
https://www.ncbi.nlm.nih.gov/pubmed/20232132
http://dx.doi.org/10.1007/s10519-010-9348-y

Ejemplares similares