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“Forward Genetics” as a Method to Maximize Power and Cost-Efficiency in Studies of Human Complex Traits
There is increasing interest in methods to disentangle the relationship between genotype and (endo)phenotypes in human complex traits. We present a population-based method of increasing the power and cost-efficiency of studies by selecting random individuals with a particular genotype and then asses...
Autores principales: | Boks, M. P. M., Derks, E. M., Dolan, C. V., Kahn, R. S., Ophoff, R. A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886904/ https://www.ncbi.nlm.nih.gov/pubmed/20232132 http://dx.doi.org/10.1007/s10519-010-9348-y |
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