Vaccinia virus lacking the Bcl-2-like protein N1 induces a stronger natural killer cell response to infection

The vaccinia virus (VACV) N1 protein is an intracellular virulence factor that has a Bcl-2-like structure and inhibits both apoptosis and signalling from the interleukin 1 receptor, leading to nuclear factor kappa B activation. Here, we investigated the immune response to intranasal infection with a...

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Detalles Bibliográficos
Autores principales: Jacobs, Nathalie, Bartlett, Nathan W., Clark, Richard H., Smith, Geoffrey L.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2008
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886957/
https://www.ncbi.nlm.nih.gov/pubmed/18931086
http://dx.doi.org/10.1099/vir.0.2008/004119-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886957/
https://www.ncbi.nlm.nih.gov/pubmed/18931086
http://dx.doi.org/10.1099/vir.0.2008/004119-0

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